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Exosomes Treatment: The Next Generation of Skin & Hair Rejuvenation

Many people seeing the word “Exosomes” for the first time assume it’s something complicated or experimental. In reality, Exosomes are simply tiny natural messengers that our own cells produce every day. They help the skin communicate, repair, and stay balanced.

This treatment is now used in cosmetic clinics worldwide as a regenerative, non-surgical option to support healthier skin and revitalised hair — especially when paired with medical-grade microneedling.


This article explains what Exosomes are, how they work, what they can support, and who typically considers this treatment.



Exosome cell

What Are Exosomes?

Exosomes are microscopic vesicles naturally released by cells. Think of them as tiny delivery capsules that carry:

  • Growth factors

  • Peptides

  • Lipids and amino acids

  • Cellular signalling molecules


Their job is to assist with communication between cells — especially during repair, regeneration, and inflammation-control processes.


They are not stem cells and do not change DNA.They simply carry messages that help the skin behave more efficiently.


Scientific reference frameworks:Research from organisations such as NIH, Science Magazine, and DermapenWorld clinical partners recognises Exosomes as a promising regenerative tool in dermatology, wound-care, inflammation modulation, and tissue restoration.


Why Are Exosomes Used in Aesthetic Treatments?


When applied during microneedling, Exosomes can help support the skin’s natural repair process at a deeper level.


Clients typically consider the treatment for:

  • Dull or uneven skin tone

  • Skin texture concerns

  • Signs of ageing such as dryness or fine lines

  • Pigmentation irregularities

  • Post-inflammatory changes

  • Scalp health, thinning hair, or weak density


Because Exosomes are combined with Dermapen4 medical microneedling, the micro-channels created allow the serum to be delivered more effectively.


How the Treatment Works

  1. Consultation – Your skin or scalp concerns are assessed.

  2. Dermapen4 Microneedling – Creates tiny micro-channels to stimulate natural repair.

  3. Application of Exosome Serum – A specialised formula containing biomimetic exosomes (HLA-G complex) is delivered through the micro-channels.

  4. Targeted Regeneration – The serum supports hydration, barrier repair, texture improvement, and natural cellular communication.


This method avoids injections, has minimal downtime, and is suitable for most skin types.


Benefits Clients Commonly Notice

(General, non-therapeutic, TAPS-compliant)

  • Smoother, more refined texture

  • Healthier, more hydrated skin

  • Brighter, more even complexion

  • Improved appearance of fine lines

  • Reduced visible redness or uneven tone

  • Stronger, healthier-looking hair and scalp support

Results build gradually over multiple sessions.



Exosomes benefits for hair and skin

Exosomes for Hair & Scalp Health

Exosomes used in conjunction with Dermapen4 can support:

  • Improved scalp condition

  • Better-looking density

  • Reduced appearance of thinning

  • Support for hair vitality


A course of 3+ treatments is generally recommended, with at-home tonic available to maintain results.


Are Exosomes Safe?

Clinic4O2 uses DermapenWorld Dp Dermaceuticals exosome technology — an internationally recognised, ethically sourced, HLA-G immune-tolerant formulation.


Key safety notes:

  • No human DNA

  • Not a stem cell treatment

  • No live cells

  • No animal serum derivatives

  • Designed for cosmetic topical use only


This aligns with TAPS standards and New Zealand appearance medicine guidelines.


Who Is Not Suitable?

This treatment may not be suitable for individuals who:

  • Are pregnant or breastfeeding

  • Have active infections or open skin lesions

  • Have known allergies to serum components

  • Have certain autoimmune or inflammatory conditions


A consultation is essential to confirm suitability.


Close-up photo of model after treatment in clinic4O2 with glowing skin and healthy hair

How Many Sessions Are Recommended?


For best results, most clients undertake:

  • 3 sessions spaced 3–4 weeks apart

  • Followed by maintenance sessions if desired

For hair: Use of an Exosome Hair Tonic is recommended between treatments.




Treatment Options at Clinic4O2

1. Exosomes Needling – Skin Face / Neck / Chest• $500 per session• Concession of 3: $1350

2. Exosomes Needling – Hair • $400 per session• Concession of 3: $1050

3. Exosomes Skin + Hair Combo • $800 per session• Concession of 3: $2100


Why Choose Clinic4O2

  • Medical-grade Dermapen4 device

  • TAPS-compliant, transparent guidelines

  • Carefully selected regenerative serums

  • Personalised treatment plans for skin and scalp

  • Professional, practitioner-led care


Ready to Learn More?

If you’re curious about whether Exosomes could support your skin or hair concerns, book a consultation:



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